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Symbol
Name
ID
Tnfsf15
tumor necrosis factor (ligand) superfamily, member 15
MGI:2180140
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
abnormal dendritic cell differentiation
small intestinal inflammation
decreased germinal center B cell number
decreased plasma cell number
decreased B cell number
increased NK cell number
increased CD4-positive, alpha-beta memory T cell number
decreased T follicular helper cell number
increased CD8-positive, alpha-beta memory T cell number
decreased T cell number
decreased IgG2a level
decreased IgG2b level
decreased IgG level
lymph node hypoplasia
increased interferon-gamma secretion
increased interleukin-17 secretion
decreased susceptibility to experimental autoimmune encephalomyelitis
decreased susceptibility to induced arthritis
Availability Mouse Genotype
Tnfsf15tm1Cdon/Tnfsf15tm1Cdon
Tnfsf15tm1Hluo/Tnfsf15tm1Hluo *
Tnfsf15tm1Lex/Tnfsf15tm1Lex
Tg(Csf1r-Tnfsf15,-EGFP)#Targ/0
Tg(Lck-Tnfsf15,-EGFP)#Targ/0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory